I’m curious to understand what the readers of radiologypics.com know about ionizing radiation, so I’ve created a few questions that I’d like to get your answers to below.
History: infant who died shortly after birth Osteogenesis imperfecta (OI), also known as brittle bone disease, is a congenital bone disorder characterized by brittle bones that are prone to fracture. People with OI are born with defective connective tissue, or without the ability to make it, usually because of a deficiency of type I collagen. On … Continue reading
History: 3 year old male with palpable left sided abdominal mass Wilms’ tumor is the most common renal malignancy and solid abdominal malignancy of childhood. The median age of patients affected by Wilms’ tumor is 3 years old. Usually Wilms’ tumor presents as a large abdominal mass, and 10% of cases are bilateral. Wilms’ tumor … Continue reading
History: 4 day old baby with apnea The germinal matrix is the site of proliferating neuronal and glial precursors in the developing brain, which is located above the caudate nucleus in the floor of the lateral ventricle and caudothalamic groove. The germinal matrix contains a rich network of fragile thin-walled blood vessels. Hence the microcirculation in … Continue reading
History: 6 year old male with abdominal pain Unfortunately, this is a case of metastatic neuroblastoma in a 6 year old male which was diagnosed initially on MRI. Neuroblastoma is the most common extracranial solid malignancy in children, and the third most common overall cancer in children. They most commonly arise from the adrenal medulla … Continue reading
History: 16 year old with abdominal pain This is a case of perforated appendicitis. Appendicitis usually occurs due to obstruction of the appendix at its origin from the cecum, in this case due to an appendicolith. This causes build up of secretions and mucus within the lumen of the appendix, which then dilates. The resultant … Continue reading
History: 13 year old female with pelvic pain This is a case of a bicornuate uterus with hydrosalpinx of the right fallopian tube. Read about Imaging of Mullerian Duct Anomalies. Uterine didelphys ultrasound.
History: 14 year old female with right lower quadrant pain This is the appearance of an ovarian dermoid cyst on MRI, also known as a mature teratoma. The name teratoma gives a clue as to the histology of the dermoid cyst, usually containing parenchymal cell types from all three germ cell layers (mesoderm, endoderm, and … Continue reading
History: 14 year old female with right lower qaudrant pain This is the appearance of pediatric appendicitis on MRI. Intravenous gadolinium contrast aids in visualization of the appendix (as seen in the third image above, the LAVA-Flex sequence MRI). MRI has recently been a hot topic of research in the diagnosis of pediatric appendicitis in … Continue reading
History: Not moving left leg, flexion contracture at the knee. Other past medical history includes hyperbilirubinemia at birth, autoimmune hepatitis, sensorineural hearing loss and global developmental delay. Neonatal Onset Multisystem Inflammatory Disease (NOMID) was first described by Prier and Griscelli in 1987 and has also been referred to as chronic infantile neurologic, cutaneous and articular syndrome (CINCA). It is a rare genetic disorder on the spectrum of cryopyrin associated periodic syndromes (CAPS). NOMID is … Continue reading