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Xanthogranulomatous Pyelonephritis

History: 20 year old female with back pain and urinary tract infection.  This is a case of xanthogranulomatous pyelonephritis, which is defined as a chronic infection of the kidney and surrounding structures, destruction of renal parenchyma, and infiltration with lipid-laden macrophages. It is the lipid-laden macrophages which characteristically give this entity its name “xanthogranulomatous.” Xanthos … Continue reading

Skull Metastases

History: Middle aged man with headache.  This is a case of lung cancer metastases to the skull. Lung cancer, like breast cancer, can produce both lytic and sclerotic bone metastases. Read about other cancers and the bone metastases they produce. Thank you to Dra. Pilar Rodríguez Pérez from Spain for submitting this case. See this patient’s … Continue reading

Right Upper Lobe Lung Cancer with Rib Metastasis

History: Middle aged man with a history of smoking, cough, and chest pain.  This is a case of Lung Cancer with a metastasis to the contralateral ribs. Any spiculated lung mass in a patient with a history of smoking should be considered lung cancer until proven otherwise. Read this article here regarding the differential diagnosis … Continue reading