History: 65 year old male with jaundice.
This is a Klatskin tumor causing bile duct obstruction and biliary dilatation. A Klatskin tumor is a cholangiocarcinoma that arises at near the confluence of the right and left hepatic ducts and causes obstruction of bile duct outflow, leading to biliary dilatation as seen in the second image above. Other causes of biliary dilatation may include pancreatic carcinoma, choledocholithiasis, chronic pancreatitis, primary sclerosing cholangitis, and others. Read about mimics of cholangiocarcinoma here.
Cholangiocarcinoma is most common in patients older than 60, has a slight male predominance, and is more common in Asia. The five year survival unfortunately is very poor for extrahepatic cholangiocarcinoma, on the order of 1-2%.