Lytic Bone Lesion Mnemonic – FEGNOMASHIC

This is a commonly used mnemonic to recall the differential diagnosis of lytic bone lesions:

F – fibrous dysplasia, fibrous cortical defect
E – enchondroma (of the tibia here or of a phalanx here), eosinophilic granuloma
G – giant cell tumor
N – non-ossifying fibroma
O – osteoblastoma
M – metastases, myeloma
A – aneurysmal bone cyst
S – solitary bone cyst (unicameral bone cyst)
H – hyperparathyroidism
I – infection (osteomyelitis)
C – chondroblastoma and chondromyxoid fibroma

Some reorganize FEGNOMASHIC into FOG MACHINES. They both work equally well, of course.