History: 50 year old female with abdominal pain with an incidental finding.
Adenomyomatosis is focal gallbladder wall thickening secondary to hyperplastic smooth muscle proliferation and exaggeration of the Rokitansky-Aschoff sinuses. It is usually asymptomatic, incidental, and of little clinical importance. Cholecystectomy can be performed if patients are symptomatic. The differential diagnosis includes adenomatous polyp, and much less likely in this case gallbladder carcinoma and chronic cholecystitis.
Read about the differential diagnosis of gallbladder wall thickening here.