History: 60 year old male with left sided chest pain.
This is a case of pathology proven metastatic malignant mesothelioma. These are tumors of the pleura, and are most likely secondary to long-term asbestos exposure, in which there is a dose-response relationship and typically a latent period of 30-45 years. Asbestos plaques are not a precursor to malignant mesothelioma. While the aggressiveness of this particularly mass makes malignant mesothelioma the likely diagnosis, the differential includes metastatic adenocarcinoma, empyema, malignant thymoma, splenosis, and lymphoma.